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Administering low-dose intravenous ketamine transforms multimodal general anesthesia by targeting central pain pathways before surgical stimulation begins. Ketamine functions as a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, dampening dorsal horn wind-up and preventing acute central sensitization (Peltoniemi et al., 2016). When combined synergistically with gamma-aminobutyric acid (GABA) receptor agonists like propofol, it produces reliable hypnotic depth and somatic analgesia
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🫐What is general Anesthesia? I ask this question every now and then in patients are often confused as of what it actually entails now general Anesthesia involves giving medication to the point where you are completely asleep and comfortable, but this can impact your ability to breathe on your own therefore, it requires us to place a breathing tube which allows us to breathe for you and to give you Anesthesia gas. Once the surgery is done, the breathing tube comes out, we wake you up, and we bri
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