A loss of the foot processes of the podocytes (i.e., podocyte effacement) is a hallmark of minimal change disease, which has therefore sometimes been called foot process disease.

Podocyte loss defines many forms of glomerular disease, which are challenging to treat given the highly specialized, differentiated state of these cells. In this review, we focus on podocytes and …

Nov 23, 2025 · Podocyte failure underlies several significant kidney diseases, including diabetic nephropathy, which is the most common cause of kidney failure worldwide. In diabetic …

Jul 22, 2025 · Discover the podocyte, a specialized cell forming the kidney’s final filter. Its intricate structure is key to preventing protein loss and kidney disease.

The podocyte is a highly specialized visceral epithelial cell that forms the outermost layer of the glomerular capillary loop and plays a critical role in the maintenance of the glomerular filtration …

May 8, 2025 · Given their critical role in filtration, it is not surprising that podocyte injury, podocyte loss and changes to the podocyte ultrastructure result in a range of chronic kidney diseases...

Each podocyte extends primary cytoplasmic processes around glomerular capillaries. Each primary process extends numerous secondary processes, called foot processes, which …

Apr 24, 2025 · Podocyte loss defines many forms of glomerular disease, which are challenging to treat given the highly specialized, differentiated state of these cells. In this review, we focus on …

Nov 3, 2025 · ABSTRACT Podocytopathies encompass a spectrum of glomerular disorders driven by structural and functional impairments in podocytes: specialized cells critical for maintaining …

We address the principles of podocyte development and of their terminal differentiation. We will summarize experimental data that demonstrate how many podocytes we have and what …