Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing RNA in eukaryotic cells and eventually giving rise to proteins. Scientists ...
Charles Darwin described evolution as "descent with modification." Genetic information in the form of DNA sequences is copied and passed down from one generation to the next. But this process must ...
Hfq is a pleitropic actor that serves as stress response and virulence factor in the bacterial cell. To execute its multiple functions, Hfq assembles into symmetric torus-shaped hexamers. Extending ...
Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a ...
For the first time, researchers from the Max Planck Institute (MPI) for Multidisciplinary Sciences and the University Medical Center Göttingen (UMG) have demonstrated how the Nipah virus replicates ...
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Biology’s four-letter DNA alphabet just expanded to eight
An essential cellular enzyme successfully transcribed synthetic DNA letters, bringing expanded genetic codes closer to biological use.
The overall goal of this project is to identify new therapies that target influenza virus replication. The global health burden of annual influenza epidemics coupled with the emergence of highly ...
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