A research team led by Prof. Chen Yan and Prof. Yang Lifeng from the Shanghai Institute of Nutrition and Health of the Chinese Academy of Sciences revealed a physiological function of monocarboxylate ...

A new review in the Journal of Translational Medicine details how lactate and protein lactylation act as a double-edged sword ...

It increases during intense exercise. But that is not all there is to it.Running at full speed.Lifting heavy objects ...

The same fundamental biological mechanism that helps athletes develop endurance on a treadmill may someday be tapped into by doctors in intensive care units to save and improve the lives of patients ...

However, using isotope tracers, first in lab animals and then in people, Brooks found that we make and use lactate all the time. This is what he calls the lactate shuttle, where "producer" cells make ...

Athletic trainers and competitive athletes think of lactate as the cause of muscle fatigue, reduced performance, and pain. New research suggests that’s not the case. In the journal Cell Metabolism, ...

New article published in Cell Metabolism reviews the history of the misunderstanding of lactate, often called lactic acid, a small molecule that plays a big role in metabolism. Typically lactate is ...

The requirement for metabolic efficiency forces cancer cells to generate sufficient energy equivalents to support their high proliferative activity. One cycle of glycolysis supplies cells with two ...

When George Brooks first began investigating lactate, or lactic acid, sports physiologists saw it as a muscle poison that lowered performance. His research over decades has reversed that picture, ...

George Brooks has been trying to reshape thinking about lactate – in the lab, the clinic and on the training field – for more than 40 years, and finally, it seems, people are listening. Lactate, it’s ...