Over the years, chemical biology methods have made an important contribution to the study of integral membrane proteins. A key modern approach is genetic code expansion (GCE), which makes it possible ...

In my first semester of graduate school at Tufts University, I sat across from a young professor as he pitched me on joining his lab to work on genetic code expansion (GCE). Even though I'd just ...

The genetic code is the recipe for life, and provides the instructions for how to make proteins, generally using just 20 amino acids. But certain groups of microbes have an expanded genetic code, in ...

Expanded genetic alphabets with synthetic nucleotides can greatly increase the chemical diversity of nucleic acids, enabling new molecular functions. Because cellular transcription is executed by ...

Peking University, June 27, 2025: To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University ...