Antibody-producing plasmablasts (PB) and plasma cells (PC) are critical for humoral immunity, autoimmunity and vaccine responses. Despite the importance of environmental stressors in regulating ...

A small longitudinal study of 12 transplant recipients found that two-dimensional B-cell receptor analysis revealed ...

Teleost fish represent the earliest vertebrates possessing an adaptive immune system underpinned by B lymphocytes. In these species, B cells develop primarily within the anterior kidney and spleen and ...

In a recent Review published in the journal Science Immunology, researchers summarize recent advances in memory B cell biology with implications for vaccine design, driven by new understanding of ...

A retrospective study of 109 patients finds that CD19-directed CAR T-cell therapy reduces nodal and extranodal lymphoma ...

Members of the Immune Systems & Stem Cells research area are interested in understanding how immune systems and stem cells regulate organismal health and disease. We investigate the beneficial immune ...

While birthday candles measure the number of years someone has lived, they don't always tell the full story about someone's health. Two people born on the same day can have immune systems that age ...