In the 20 years since the FDA’s approval of rituximab for rheumatoid arthritis, trials and real-world use of B-cell depleting therapies have resulted in surprising successes and unexpected setbacks in ...

A research team led by associate professors Yohei Funakoshi and Kimikazu Yakushijin and Professor Hironobu Minami of the ...

The pGen-SHM plot combines BCR generation probability and somatic hypermutation to track humoral immune recovery after stem cell transplantation. The approach has revealed distinct maturation patterns ...

B-cell acute lymphoblastic leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most common childhood cancer, making up 35% of pediatric cancer cases, but it ...

Stanford Medicine researchers developed a two-part molecule that reprograms a key protein in B-cell lymphoma, causing ...

Recognition of mixed autoimmune hemolytic anemia can help clinicians avoid treatment strategies appropriate for only warm or cold disease.